The Rabbit Anti-IkappaB-alpha Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to NFKBIA. This antibody recognizes Homo Sapiens, Human, Mouse, Rat, and Non-Human Primate antigen. The Rabbit Anti-IkappaB-alpha Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
NFKB inhibitor alpha (NFKBIA) Homo sapiens This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011]