MyBioSource.com's LIM Kinase 1 Rabbit mAb is a Rabbit monoclonal antibody. The LIM Kinase 1 Rabbit mAb Antibody was generated using LIM domain kinase 1, and LIMK1 as the antigen. It reacts with Homo Sapiens, Human, and Mouse. This antibody has been shown to work in applications such as: Western Blot.
Description
Protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. Stimulates axonal outgrowth and may be involved in brain development. Isoform 3 has a dominant negative effect on actin cytoskeletal changes