The FOLR1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Folate receptor alpha, and FOLR1. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The FOLR1 Antibody has been shown to work in the following applications: Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation