MyBioSource.com's Toll-Like Receptor 9 Rabbit mAb is a Rabbit monoclonal antibody. The Toll-Like Receptor 9 Rabbit mAb Antibody was generated using TLR9 as the antigen. It reacts with Homo Sapiens, and Human. This antibody has been shown to work in applications such as: Western Blot.
Description
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response