MyBioSource.com's Rabbit Anti-alpha Synuclein Antibody is a Rabbit monoclonal antibody. The Rabbit Anti-alpha Synuclein Antibody was generated using Snca, and Synuclein alpha as the antigen. It reacts with Homo Sapiens, Human, Mouse, and Rat. This antibody has been shown to work in applications such as: Immunocytochemistry, Immunofluorescence, and Western Blot.
Description
May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation. Genetic alterations of SNCA resulting in aberrant polymerization into fibrils, are associated with several neurodegenerative diseases (synucleinopathies)