The Rabbit Anti-JAK3 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to JAK3, and Janus kinase 3. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The Rabbit Anti-JAK3 Antibody has been shown to work in the following applications: Western Blot.
Description
The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008]