MyBioSource.com's MCOLN2 Polyclonal Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The MCOLN2 Polyclonal Antibody was generated using MCOLN2, and mucolipin TRP cation channel 2 as the antigen and it reacts with Homo Sapiens, Human, and Rat.
Description
Mucolipins constitute a family of cation channel proteins with homology to the transient receptor potential superfamily. In mammals, the mucolipin family includes 3 members, MCOLN1 (MIM 605248), MCOLN2, and MCOLN3 (MIM 607400), that exhibit a common 6-membrane-spanning topology. Homologs of mammalian mucolipins exist in Drosophila and C. elegans. Mutations in the human MCOLN1 gene cause mucolipodosis IV (MIM 262650)(Karacsonyi et al., 2007 [PubMed 17662026]).[supplied by OMIM, Sep 2009]