The ASCC1 rabbit pAb Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ASCC1. This antibody recognizes Homo Sapiens, Human, and Mouse antigen. The ASCC1 rabbit pAb Antibody has been shown to work in the following applications: Western Blot.
Description
This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]