MyBioSource.com's XPD Rabbit mAb is a Rabbit monoclonal antibody. The XPD Rabbit mAb Antibody was generated using ERCC2 as the antigen. It reacts with Homo Sapiens, and Human. This antibody has been shown to work in applications such as: Immunocytochemistry, Immunofluorescence, and Western Blot.
Description
ATP-dependent 5'-3' DNA helicase, component of the core-TFIIH basal transcription factor. Involved in nucleotide excision repair (NER) of DNA by opening DNA around the damage, and in RNA transcription by RNA polymerase II by anchoring the CDK-activating kinase (CAK) complex, composed of CDK7, cyclin H and MAT1, to the core-TFIIH complex. Involved in the regulation of vitamin-D receptor activity