The PRG4 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to PRG4, and proteoglycan 4. This antibody recognizes Homo Sapiens, Human, and Rat antigen. The PRG4 Polyclonal Antibody has been shown to work in the following applications: Western Blot.
Description
The protein encoded by this gene is large proteoglycan that is synthesized by chondrocytes located at the surface of articular cartilage and by some synovial lining cells. This protein contains both chondroitin sulfate and keratan sulfate glycosaminoglycans. It functions as a boundary lubricant at the cartilage surface and contributes to the elastic absorption and energy dissipation of synovial fluid. Mutations in this gene result in camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Alternative splicing results in multiple transcript variants