The Thioredoxin Reductase 1 Rabbit mAb Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to thioredoxin reductase 1, and TXNRD1. This antibody recognizes Homo Sapiens, Human, and Mouse antigen. The Thioredoxin Reductase 1 Rabbit mAb Antibody has been shown to work in the following applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, Immunohistochemistry - frozen, Immunoprecipitation, and Western Blot.
Description
Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid