The MRCKB Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CDC42BPB. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The MRCKB Antibody has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration. Regulates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2. In concert with MYO18A and LURAP1, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. Phosphorylates PPP1R12A