MyBioSource.com's Calponin 1 Rabbit mAb is a Rabbit monoclonal antibody. The Calponin 1 Rabbit mAb Antibody was generated using Calponin 1, and CNN1 as the antigen. It reacts with Homo Sapiens, Human, Mouse, Rat, Canine, and Porcine. This antibody has been shown to work in applications such as: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Calponin regulates smooth muscle cell contraction and is a marker of smooth muscle cell differentiation. Calponin, an Actin- and Tropomyosin-binding protein, is characterized as an inhibitory factor of smooth-muscle actomyosin activity. Calponin is implicated in the regulation of smooth muscle contraction through its interaction with F-Actin and inhibition of the Actin-activated MgATPase activity of phosphorylated Myosin