The Mouse Anti-Receptor/PVR Antibody from MyBioSource.com is a Mouse Monoclonal antibody to PVR, and PVR cell adhesion molecule. This antibody recognizes Homo Sapiens, Human, and Mouse antigen. The Mouse Anti-Receptor/PVR Antibody has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
CD155 (cluster of differentiation 155) also known as the poliovirus receptor is a protein that in humans is encoded by the PVR gene. The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene