MyBioSource.com's Phospho-Smad3 (Ser423/425) Rabbit mAb is a Rabbit monoclonal antibody. The Phospho-Smad3 (Ser423/425) Rabbit mAb Antibody was generated using SMAD3 as the antigen. It reacts with Homo Sapiens, Human, Rat, and Hamster. This antibody has been shown to work in applications such as: Western Blot.
Description
Smad3 transcription factor phosphorylated and activated by TGF-beta-type receptors. A receptor-regulated Smad (R-smad). Binds directly to consensus DNA-binding elements in the promoters of target genes. In mouse required for establishemnt of the mucosal immune response and proper development of skeleton