The SETDB2 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to SET domain bifurcated histone lysine methyltransferase 2, and SETDB2. This antibody recognizes Mouse, and Rat antigen. The SETDB2 Polyclonal Antibody has been shown to work in the following applications: Western Blot.
Description
This gene encodes a member of a family of proteins that contain a methyl-CpG-binding domain (MBD) and a SET domain and function as histone methyltransferases. This protein is recruited to heterochromatin and plays a role in the regulation of chromosome segregation. This region is commonly deleted in chronic lymphocytic leukemia. Naturally-occuring readthrough transcription occurs from this gene to the downstream PHF11 (PHD finger protein 11) gene. Alternative splicing results in multiple transcript variants