The GAB2 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to GAB2. This antibody recognizes Homo Sapiens, Human, and Mouse antigen. The GAB2 Polyclonal Antibody has been shown to work in the following applications: Western Blot.
Description
This gene is member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene