MyBioSource.com's Histone H2A.Z Rabbit mAb is a Rabbit monoclonal antibody. The Histone H2A.Z Rabbit mAb Antibody was generated using H2A.Z variant histone 1, and H2AZ1 as the antigen. It reacts with Homo Sapiens, Human, Mouse, and Rat. This antibody has been shown to work in applications such as: Western Blot.
Description
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling