The Rabbit Anti-Thymidine Kinase 2/TK2 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to Thymidine Kinase 2, and TK2. This antibody recognizes Homo Sapiens, and Human antigen. The Rabbit Anti-Thymidine Kinase 2/TK2 Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, Flow Cytometry, and Western Blot.
Description
Thymidine kinase 2, mitochondrial is a protein that in humans is encoded by the TK2 gene. This gene encodes a deoxyribonucleoside kinase that specifically phosphorylates thymidine, deoxycytidine, and deoxyuridine. The encoded enzyme localizes to the mitochondria and is required for mitochondrial DNA synthesis. Mutations in this gene are associated with a myopathic form of mitochondrial DNA depletion syndrome. Alternate splicing results in multiple transcript variants encoding distinct isoforms, some of which lack transit peptide, so are not localized to mitochondria