The ITGA2B Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ITGA2B. This antibody recognizes Homo Sapiens, Human, and Mouse antigen. The ITGA2B Polyclonal Antibody has been shown to work in the following applications: Western Blot.
Description
This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia