MyBioSource.com's Anti-Alivin1 (AMIGO2) Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The Anti-Alivin1 (AMIGO2) Antibody was generated using AMIGO2 as the antigen and it reacts with Mouse, and Rat.
Description
Alivin 1 rabbit polyclonal primary antibody from the lab is produced in-house. It detects mouse and rat Alivin 1 and is antigen affinity purified. It is great for use in WB.
A novel primary response gene, Alivin 1 (ali1), is an activity-dependent gene and promotes survival of neurons. Sequence analyses reveal that rat, mouse, and human Ali1 proteins contain seven leucine-rich repeats, one IgC2-like loop and a transmembrane domain, and display homology to Kek and Trk families. Results suggest that expression of ali1 promotes depolarization-dependent survival of the granule neuron. Mouse ali1 was mapped to a locus approximately 55.3 cM from the centromere on chromosome 15 that is syntenic to positional candidate loci for familial Alzheimer's disease type 5 and Parkinson's disease 8 on human chromosome 12