MyBioSource.com's Rabbit Anti-Histone H4 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The Rabbit Anti-Histone H4 Antibody was generated using H4 clustered histone 15, H4 histone 16, and H4C15 as the antigen and it reacts with Homo Sapiens, Human, Mouse, and Rat.
Description
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element