The JNK1/3 Rabbit mAb Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to MAPK8. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The JNK1/3 Rabbit mAb Antibody has been shown to work in the following applications: Immunoprecipitation, and Western Blot.
Description
The stress-activated protein kinase/Jun-amino-terminal kinase SAPK/JNK is potently and preferentially activated by a variety of environmental stresses including UV and gamma radiation, ceramides, inflammatory cytokines, and in some instances, by growth factors and GPCR agonists. As with the other MAPKs, the core signaling unit is composed of a MAPKKK, typically MEKK1-MEKK4, or by one of the mixed lineage kinases (MLKs), which phosphorylate and activate MKK4/7