The Cleaved-Caspase 6 p18 Rabbit pAb Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CASP6, and Caspase 6. This antibody recognizes Homo Sapiens, Human, and Rat antigen. The Cleaved-Caspase 6 p18 Rabbit pAb Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Caspase-6 (Mch2) is one of the major executioner caspases functioning in cellular apoptotic processes. Upon apoptotic stimulation, initiator caspases such as caspase-9 are cleaved and activated. The activated upstream caspases further process downstream executioner caspases, such as caspase-3 and caspase-6, by cleaving them into large and small subunits, thereby initiating a caspase cascade leading to apoptosis. One of the major targets for caspase-6 is the membrane associated protein lamin A