MyBioSource.com's Rabbit Anti-NFkappaB-p65 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: EIA, Immunoassay, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot. The Rabbit Anti-NFkappaB-p65 Antibody was generated using RELA as the antigen and it reacts with Homo Sapiens, Human, Mouse, Rat, and Non-Human Primate.
Description
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the Cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFkappaB1 or NFkappaB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFkappaB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]