MyBioSource.com's Phospho-EGFR (Tyr1068) Rabbit mAb is a Rabbit monoclonal antibody. The Phospho-EGFR (Tyr1068) Rabbit mAb Antibody was generated using EGFR, and epidermal growth factor receptor as the antigen. It reacts with Homo Sapiens, Human, and Mouse. This antibody has been shown to work in applications such as: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Receptor for epidermal growth factor (EGF) and related growth factors including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. A single-pass transmembrane tyrosine kinase. Ligand binding to this receptor results in receptor dimerization, autophosphorylation (in trans), activation of various downstream signaling molecules and lysosomal degradation. Can be phosphorylated and activated by Src