The Phospholamban Rabbit mAb Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to Phospholamban, and PLN. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The Phospholamban Rabbit mAb Antibody has been shown to work in the following applications: Immunohistochemistry, Immunohistochemistry - fixed, Immunoprecipitation, and Western Blot.
Description
Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca2+. Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. ATP2A2 inhibition is alleviated by PLN phosphorylation