The TYK2 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to tyk2. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The TYK2 Polyclonal Antibody has been shown to work in the following applications: Immunofluorescence, and Western Blot.
Description
This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E