MyBioSource.com's Geminin Rabbit mAb is a Rabbit monoclonal antibody. The Geminin Rabbit mAb Antibody was generated using geminin DNA replication inhibitor as the antigen. It reacts with Homo Sapiens, and Human. This antibody has been shown to work in applications such as: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
Inhibits DNA replication by preventing the incorporation of MCM complex into prereplication complex (pre-RC). It is degraded during the mitotic phase of the cell cycle. Its destruction at the metaphase-anaphase transition permits replication in the succeeding cell cycle