MyBioSource.com's Presenilin 1 Rabbit mAb is a Rabbit monoclonal antibody. The Presenilin 1 Rabbit mAb Antibody was generated using Presenilin 1, and PSEN1 as the antigen. It reacts with Homo Sapiens, Human, Mouse, and Rat. This antibody has been shown to work in applications such as: Flow Cytometry, and Western Blot.
Description
Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity