MyBioSource.com's C1QA Rabbit mAb is a Rabbit monoclonal antibody. The C1QA Rabbit mAb Antibody was generated using C1QA as the antigen. It reacts with Homo Sapiens, Human, and Rat. This antibody has been shown to work in applications such as: Immunohistochemistry, and Western Blot.
Description
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes