The PIAS1 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to PIAS1. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The PIAS1 Polyclonal Antibody has been shown to work in the following applications: Western Blot.
Description
This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. This protein plays a central role as a transcriptional coregulator of numerous cellular pathways includign the STAT1 and nuclear factor kappaB pathways. Alternate splicing results in multiple transcript variants