Rabbit Anti-p23/PTGES3 Antibody from MyBioSource.com

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Rabbit Anti-p23/PTGES3 Antibody

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MyBioSource.com's Rabbit Anti-p23/PTGES3 Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot.

Description

PTGES3 (Prostaglandin E Synthase 3) is a Protein Coding gene. The PTGES3 gene, located on 12q13.3, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog. This gene encodes an enzyme that converts prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). This protein functions as a co-chaperone with heat shock protein 90 (HSP90), localizing to response elements in DNA and disrupting transcriptional activation complexes. Alternative splicing results in multiple transcript variants. PTGES3 is widely expressed in the ovary, endometrium, and other tissues. Among its related pathways are Arachidonic acid metabolism and Cytochrome P450-arranged by substrate type. 226 organisms have orthologs with the human gene PTGES3