MyBioSource.com's Melanocyte Protein PMEL Rabbit mAb is a Rabbit monoclonal antibody. The Melanocyte Protein PMEL Rabbit mAb Antibody was generated using PMEL as the antigen. It reacts with Homo Sapiens, and Human. This antibody has been shown to work in applications such as: Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity