The Rabbit Anti-Collagen VI/COL6A2 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to COL6A2. This antibody recognizes Homo Sapiens, and Human antigen. The Rabbit Anti-Collagen VI/COL6A2 Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, Immunohistochemistry, and Western Blot.
Description
Collagen alpha-2(VI) chain is a protein that in humans is encoded by the COL6A2 gene. This gene encodes one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. The product of this gene contains several domains similar to von Willebrand Factor type A domains. These domains have been shown to bind extracellular matrix proteins, an interaction that explains the importance of this collagen in organizing matrix components. Mutations in this gene are associated with Bethlem myopathy and Ullrich scleroatonic muscular dystrophy. Three transcript variants have been identified for this gene