The Rabbit Anti-Ku-70 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to XRCC6. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The Rabbit Anti-Ku-70 Antibody has been shown to work in the following applications: EIA, Immunoassay, ELISA, and Western Blot.
Description
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that requiredfor double-strand break repair, transposition, and V (D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008]