MyBioSource.com's MIB1/DIP1 Rabbit mAb is a Rabbit monoclonal antibody. The MIB1/DIP1 Rabbit mAb Antibody was generated using MIB E3 ubiquitin protein ligase 1, and MIB1 as the antigen. It reacts with Homo Sapiens, Human, and Mouse. This antibody has been shown to work in applications such as: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors