The Superoxide Dismutase 1 Rabbit mAb Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to SOD1, and Superoxide Dismutase 1. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The Superoxide Dismutase 1 Rabbit mAb Antibody has been shown to work in the following applications: Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
SOD1, Cu/Zn superoxide dismutase, is a major antioxidant enzyme that catalyzes the conversion of superoxide anion to hydrogen peroxide and molecular oxygen. The mechanism by which mutant SOD1 induces the neurodegeneration observed in ALS is still unclear. Mutant SOD1 proteins become misfolded and consequently oligomerize into high molecular weight species that aggregate and end up in proteinaceous inclusions