The Pyruvate Dehydrogenase E1 alpha Rabbit mAb Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to PDHA1, and pyruvate dehydrogenase E1 subunit alpha 1. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The Pyruvate Dehydrogenase E1 alpha Rabbit mAb Antibody has been shown to work in the following applications: Immunocytochemistry, Immunofluorescence, Immunoprecipitation, and Western Blot.
Description
The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). Catalyzes the removal of CO2 from pyruvate. Mutations in the ? subunits of pyruvate dehydrogenase (E1) lead to congenital defects that are usually associated with lactic acidosis, neurodegeneration and early death