MyBioSource.com's Macro H2A.1 Rabbit mAb is a Rabbit monoclonal antibody. The Macro H2A.1 Rabbit mAb Antibody was generated using macroH2A.1 histone, and MacroH2A1 as the antigen. It reacts with Mouse, and Rat. This antibody has been shown to work in applications such as: Immunocytochemistry, Immunofluorescence, and Western Blot.
Description
Involved in stable X chromosome inactivation. Inhibits the binding of transcription factors and interferes with the activity of remodeling SWI/SNF complexes. Inhibits histone acetylation by EP300 and recruits class I HDACs, which induces an hypoacetylated state of chromatin