The KAT6B Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to KAT6B. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The KAT6B Polyclonal Antibody has been shown to work in the following applications: Western Blot.
Description
The protein encoded by this gene is histone acetyltransferase and component of the MOZ/MORF protein complex. In addition to its acetyltransferase activity, the encoded protein has transcriptional activation activity in its N-terminal end and transcriptional repression activity in its C-terminal end. This protein is necessary for RUNX2-dependent transcriptional activation and could be involved in brain development. Mutations have been found in patients with genitopatellar syndrome. A translocation of this gene and the CREBBP gene results in acute myeloid leukemias. Three transcript variants encoding different isoforms have been found for this gene