MyBioSource.com's p53 (acetyl K370) Rabbit mAb is a Rabbit monoclonal antibody. The p53 (acetyl K370) Rabbit mAb Antibody was generated using TP53, and tumor protein p53 as the antigen. It reacts with Homo Sapiens, Human, Mouse, and Rat. This antibody has been shown to work in applications such as: Immunocytochemistry, Immunofluorescence, Immunoprecipitation, and Western Blot.
Description
Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy