The Cox2 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to PTGS2. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The Cox2 Polyclonal Antibody has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events,uggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis