The Histone H3 (formyl K122) Rabbit mAb Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to H3 clustered histone 1, and H3C1. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The Histone H3 (formyl K122) Rabbit mAb Antibody has been shown to work in the following applications: Immunohistochemistry, and Western Blot.
Description
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling