The MASP2 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to MASP2, and MBL associated serine protease 2. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The MASP2 Polyclonal Antibody has been shown to work in the following applications: Western Blot.
Description
This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is proteolytically processed to generate A and B chains that heterodimerize to form the mature protease. This protease cleaves complement components C2 and C4 in order to generate C3 convertase in the lectin pathway of the complement system. The encoded protease also plays a role in the coagulation cascade through cleavage of prothrombin to form thrombin. Myocardial infarction and acute stroke patients exhibit reduced serum concentrations of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed