MyBioSource.com's Rabbit Anti-Glutaredoxin 1/GLRX Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: EIA, Immunoassay, ELISA, Flow Cytometry, Immunocytochemistry, Immunofluorescence, and Western Blot. The Rabbit Anti-Glutaredoxin 1/GLRX Antibody was generated using glrx, and Glutaredoxin as the antigen and it reacts with Homo Sapiens, and Human.
Description
Glutaredoxin-1 is a protein that in humans is encoded by the GLRX gene. This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified