The Rabbit Anti-IGF1 Receptor Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to IGF1R. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The Rabbit Anti-IGF1 Receptor Antibody has been shown to work in the following applications: Immunoprecipitation, and Western Blot.
Description
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]