MyBioSource.com's Aquaporin 2 Rabbit mAb is a Rabbit monoclonal antibody. The Aquaporin 2 Rabbit mAb Antibody was generated using AQP2, and Aquaporin 2 as the antigen. It reacts with Homo Sapiens, and Human. This antibody has been shown to work in applications such as: Immunohistochemistry, Immunohistochemistry - fixed, Immunoprecipitation, and Western Blot.
Description
The basic job of aquaporin 2 is to reabsorb water from the urine while its being removed from the blood by the kidney. Aquaporin 2 is in kidney epithelial cells and usually lies dormant in intracellular vesicle membranes, but when it is needed vasopressin binds to the cell surface vasopressin receptor, activating a signaling pathway that causes the aquaporin 2 containing vesicles to fuse with the plasma membrane so the aquaporin 2 can be used by the cell