The Caspase 14 Rabbit mAb Antibody from MyBioSource.com is a Rabbit Monoclonal antibody to CASP14, and Caspase 14. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The Caspase 14 Rabbit mAb Antibody has been shown to work in the following applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, Immunoprecipitation, and Western Blot.
Description
Caspases are a family of cysteine proteases that play an essential role in carrying out apoptosis. Caspase-14, also named MICE, is a unique member of the caspase family with restricted expression; it is found in embryonic tissues and adult skin. Caspase-14 is weakly processed into p18 and p11 subunits by caspase-8. May also be responsible for proteolytic processing of filaggrin during terminal differentiation of keratinocytes