The Rabbit Anti-Cleaved PARP Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to PARP1. This antibody recognizes Homo Sapiens, and Human antigen. The Rabbit Anti-Cleaved PARP Antibody has been shown to work in the following applications: Western Blot.
Description
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes